Her subject is Walter Reed (1851-1902), the U.S. Army physician who in 1901 led a team of researchers that linked the spread of yellow fever to mosquitoes. Luckhart will speak on "He Gave to Man Control Over That Dreadful Scourge, Yellow Fever” at the awards breakfast on Tuesday, Nov. 13.
The Entomological Society of America (ESA) established the award in 1958 to honor the memory of scientists who've made outstanding contributions to entomology.
Quite familiar with Reed's work, Luckhart served as a National Research Council postdoctoral scientist at the Walter Reed Army Institute of Research, Silver Spring, Md., after completing her Ph.D. at Rutgers University, New Jersey, in 1995. She went on to accept research and teaching roles at the Uniformed Service University of the Health Sciences, Bethesda, Md. (1996-1998); Virginia Polytechnic Institute and State University, Blacksburg, Va. (1998-2004); and at UC Davis (2004-2016).
"Shirley sees her work as being part of not only her department, school, and university but of the universe of science,” said Ronald Rosenberg, associate director for science at the U.S. Centers for Disease Control's Division of Vector-Borne Diseases, who directed the entomology division at the Walter Reed Army Institute of Research when Luckhart held her postdoctoral position. “She is always interested in what other people do and seems to have innumerable collaborators. "We often spoke of what an extraordinary and brave scientist Reed was. I think Shirley Luckhart is a superb choice to honor his legacy while looking into the future."
Luckhart got her start in entomology more than 30 years ago, "and in that time her research on the biochemistry and molecular cell biology of Anopheles mosquitoes has continued the scientific progress sparked by Reed more than a century ago," related ESA in the news release. "Her work has been continuously funded by the U.S. National Institutes of Health since 1997, focused broadly on understanding the transmission of the causative agent of malaria by Anopheles mosquitoes. Many of her findings have led to interventions that block both infection and transmission, and, as a result, she has several patents in process." (See ESA news release and a list of past Founders' Memorial Award recipients and honorees.)
While at UC Davis, Luckhart held a joint appointment as a professor in the Department of Medical Microbiology and Immunology, School of Medicine, and the Department of Entomology and Nematology, College of Agricultural and Environmental Sciences. She joined the University of Idaho in 2017 as a professor in both the Department of Entomology, Nematology and Plant Pathology and the Department of Biological Sciences, and as the founding co-director of the university's Center for Health in the Human Ecosystem.
Luckhart was named a 2014 Fellow of the American Society for Tropical Medicine and Hygiene. In 2017, she received the Medical, Urban and Veterinary Award from ESA's Pacific Branch.
Entomology 2018, themed "Crossing Borders: Entomology in a Changing World" highlights the value of collaboration and cooperation across both geographic and interdisciplinary boundaries.
This year's ESA president is Michael Parrella, dean of the College of Agricultural and Life Science at the University of Idaho, and former professor and chair, UC Davis Department of Entomology and Nematology.
Molecular biologist Shirley Luckhart, who holds a joint appointment with the UC Davis School of Medicine's Department of Medical Microbiology and Immunology and the UC Davis Department of Entomology and Nematology (and soon will transition to the University of Idaho), has been named the recipient of the Medical, Urban and Veterinary Entomology Award.
Ant specialist Marek Borowiec, who received his doctorate in entomology in June 2016, studying with major professor Phil Ward, won the Systematics, Evolution, and Biodiversity Award. He is now a postdoctoral fellow at Arizona State University, Tempe.
Third-year graduate student Ralph Washington Jr., who studies with major professors Steve Nadler, professor and chair of the UC Davis Department of Entomology and Nematology, and assistant professor Brian Johnson, won the Student Leadership Award.
The three will be among the 13 award recipients honored at the PBESA meeting, April 2-5 in Portland, Ore. PBESA encompasses 11 Western U.S. states, plus several U.S. territories and parts of Canada and Mexico.
Ralph Washington Jr.
Ralph Washington Jr., who received his bachelor of science degree in entomology at UC Davis in 2010, is known as an outstanding scholar and leader. He holds a National Science Foundation Graduate Research Fellowship. He has also previously received a Gates Millennium Scholarship, a Ronald E. McNair Graduate Fellowship, and a Monsanto Graduate Student Scholarship.
Washington is active in leadership roles on the UC Davis campus, UC systemwide, and in PBESA and the Entomological Society of America (ESA). He captained the UC Davis Linnaean Games team to several first place wins at the PBESA level and then led his team in winning the national championship in both 2015 and 2016. He was an integral part of the UC Davis Student Debate Team that won the ESA's 2014 national championship. In addition, he swept first place in the Natural History Trivia Competition at the 2016 Annual Meeting of the American Society of Naturalists.
Washington's leadership activities include 2015-2016 co-chair of the UC Council of Student Body Presidents, and 2015-2016 Chair of the UC Davis Graduate Students' Association. He was named Graduate Student of the Year in 2015 and 2016 at the UC Davis Black Affirmation Awards. He is currently president of the University of California Student Association. He is active in social justice issues, including gender-based violence and misconduct, and institutional oppression.
Washington was one of nine people invited to speak at TEDxUCDavis Conference (Igniting X). "All human beings are born curious, but the wrong conditions can jeopardize that curiosity," he said, speaking on “Science, Poverty and the Human Imagination.”
“Many children in poverty grow up feeling a lack of control over their circumstances, and this severely inhibits their ability to imagine a reality other than their own,” said Washington, who grew up in an impoverished family. “Targeted science education starting from a young age can inspire and help struggling children."
Marek Borowiec, who holds a master's degree in zoology from the University of Wroclaw, Poland, joined the Phil Ward lab in 2010, receiving training as a molecular phylogeneticist and computational biologist. Borowiec is now a postdoctoral fellow in the lab of evolutionary biologist/ant specialist Christian Rabeling, Arizona State University, where he studies the genomics of speciation and evolution of social parasitism in Formica ants.
One of the highlights of Borowiec's career: last year he won the coveted George C. Eickwort Student Research Award, sponsored by the North American Section of the International Union for the Study of Social Insects (IUSSI-NAS).
“Marek is an astute and dedicated scientist, with an insightful mind, diverse interests, and trenchant drive,” wrote Phil Ward in the awards nominations packet. “Marek's Ph.D. research was motivated by a strong interest in the patterns and processes underlying the genesis of biological diversity. He explored this through a range of studies on ant systematics, phylogeny and biogeography. The principal focus was on the evolution of army ants—those charismatic and notorious creatures that have a profound ecological impact in many communities—and he showed decisively that the ‘army ant syndrome' evolved independently in the New World and Old World tropics, settling a long-standing controversy on this matter.
Borowiec has published more than 25 papers, many focusing on the phylogeny of army ants, relationships among “basal” lineages of ants, and a collaborative phylogenomic project on ants and their relatives.
He is a subject editor for ZooKeys, an innovative systematics journal, and Biodiversity Data Journal; he receives frequent requests to review manuscripts for other journals.
Shirley Luckhart was lauded for her “highly regarded expertise on molecular cell biology and biochemistry of malaria parasite transmission.” Her expertise on vector-borne diseases encompasses mosquito and black fly vectors of filarial nematodes and Lyme disease ecology as well as mosquito biology, disease pathogenesis, and transmission blocking agents for malaria.
Luckhart, who received her doctorate in entomology in 1995 from Rutgers, The State University of New Jersey, joined the UC Davis faculty in 2004 from Virginia Tech. Since 1997, the National Institutes of Health has continuously funded her research on host-parasite interactions in malaria.
She was named a Fellow of the American Society of Tropical Medicine and Hygiene in 2014. She and her colleagues drew international acclaim when Time Magazine, in 2010, named their work on a “malaria-proof” or genetically engineered mosquito as one of the “Top 50 Inventions of the Year,” ranking it No. 1 in the health category.
While most of her work has been lab-based, Luckhart has worked with collaborators in Kenya for the past 20 years and on highly productive field- and lab-based collaborative projects in Mali, Cameroon, and Colombia. Her career includes principal investigator on large awards to both national and international teams and co-director of multiple National Institutes of Health (NIH) training grants. She currently serves on the NIH Vector Biology study section and is a member of the Scientific Advisory Group for the Biodefense and Emerging Infections Research Resources Repository (BEI Resources).
For the past five years, Luckhart has chaired the national BEI Vectors Focus Group, which works with NIH's National Institute of Allergy and Infectious Diseases leadership to significantly expand vector and vector-borne pathogen resources globally. These efforts also led to the development of an independent Allied Insect Biology working group to engage scientists in trans-disciplinary workshops and collaborations across plant, animal, and human vector-borne diseases. In recognition of her efforts, Luckhart was invited to deliver the keynote address at the Keystone meeting in Taos, N.M., in May 2015.
Luckhart also received $100,000 from Grand Challenges Explorations, Bill and Melinda Gates Foundation, to advance her work in developing nutritional supplements to reverse the malaria-induced intestinal damage that contributes to the development of non-typhoidal Salmonella (NTS) bacteremia in malaria-infected children.
At UC Davis, she served as interim co-director of the Center for Vector-borne Diseases from 2014-15 and chaired the graduate level Designated Emphasis in the Biology of Vector-borne Diseases from 2012 to just recently, when she stepped down from these duties. She also directs a large collaborative insectary facility at UC Davis, providing support to vector-borne disease research programs in the School of Medicine, the College of Agricultural and Environmental Sciences, and the School of Veterinary Medicine.
Luckhart has published 93 peer-reviewed articles, with more than 2500 citations, and five book chapters. Throughout her career, she has taught and mentored nine doctoral students, who have gone on to successful careers at the state, national or international level. In recognition of her work, she received mentoring awards from the UC Davis Consortium for Women and Research (2012) and the UC Davis Graduate Student Association (2016).
Luckhart will transition to the University of Idaho, effective May 15. She and her husband, Edwin Lewis, associate dean for Agricultural Sciences in the College of Agricultural and Environmental Sciences and former vice chair of the UC Davis Department of Entomology and Nematology will expand their research programs and also co-direct the new Center for Health in the Human Ecosystem, which will focus on how the impacts of land use, including agriculture, urbanization and deforestation, interact to impact transmission and control of disease agents of people, animals and plants.
Luckhart's primary appointment is in the Department of Plant, Soil and Entomological Sciences (PSES) in the College of Agricultural and Life Sciences and her secondary appointment is in the Department of Biological Sciences. Lewis' appointment is in PSES.
Lewis won the PBESA's Integrated Pest Management Excellence Award in 2016,
Other 2017 PBESA award recipients to be honored at the PBESA meeting in Oregon:
- Pacific Branch C.W. Woodworth Award- Gerhard and Regine Gries, Simon Fraser University, Canada
- Award for Excellence in Teaching- Helen Spafford, University of Hawaii, Manoa
- Award for Excellence in Extension- Carol Black, Washington State University (WSU), Pullman
- Award for Excellence in Integrated Pest Management- Elizabeth Beers, WSU
- Physiology, Biochemistry and Toxicology Award- Ramesh Sagili, Oregon State University, Corvallis
- Plant-Insect Ecosystems Award- David Crowder, WSU
- Distinction in Student Mentoring- James Strange, USDA, Logan, Utah
- Excellence in Early Career- Sarah Woodard, UC Riverside
- John Henry Comstock Graduate Student Award- Amelia Lindsey, UC Riverside
- Entomology Team Award-- Lisa Neven, Wee Yee and Sunil Kumar, Colorado State University, Ft. Collins--for their project “Pest Risk Analyses for Temperate Fruit Flies in Exported Fruits Team”
Spotlighted are parasitologist and entomologist Shirley Luckhart, professor in the UC Davis School of Medicine's Department of Medical Microbiology and immunology and the Department of Entomology and Nematology; medical entomologist Gregory Lanzaro, professor, Department of Pathology, Microbiology and Immunology (PMI), UC Davis School of Veterinary Medicine, and an associate of the UC Davis Department of Entomology and Nematology; chemical ecologist Walter Leal, professor in the UC Davis Department of Molecular and Cellular Biology and former chair of the UC Davis Department of Entomology; virologist Lark Coffey of PMI; and UC Davis post-doctoral researcher Young-Moo Choo of the Leal's lab who discovered a receptor by dissecting mosquitoes' mouthparts and genetically testing them.
The KQED piece, drawing widespread interest, is the work of Gabriela Quirós, coordinator producer of Deep Look, KQED Science.
Luckhart said that the mosquitoes detect body heat and substances called volatile fatty acids. “The volatile fatty acids given off by our skin are quite different," Luckhart told Quirós. "They reflect differences between men and women, even what we've eaten. Those cues are different from person to person. There's probably not one or two. It's the blend that's more or less attractive.”
“Mosquitoes don't find the blood vessel randomly," Leal said, pointing out that the receptors respond to chemicals in the blood.
The receptor that the Leal lab discovered is called 4EP, and may lead to drug companies developing new mosquito repellents. “First they'd need to find a repellent against the receptors," Choo told Quirós. "Then they'd treat people's skin with it. When the mosquito tried to penetrate the skin, it would taste or smell something repulsive and fly away.”
Lanzaro said that the latest malaria statistics--more than 300 million people contracted malaria in 2015, and some 635,000 died--are "probably an underestimate."
Her presentation is part of the weekly seminars hosted by the Program in International and Community Nutrition (PICN) seminars, all held Wednesdays from 12:10 to 1 p.m. in the Foster Room (Room 1138) of Meyer Hall.
Luckhart's research includes the molecular cell biology and biochemistry of malaria parasite transmission, the functional characterization of the immunological crosstalk and cell signaling that occurs between the mosquito and the mammalian host during bloodfeeding, and the impact of endemic co-infections on malaria parasite development and transmission.
She just received the 2016 “Award for Excellence in Service to Graduate Students,” presented April 8 by the UC Davis Graduate Student Association for outstanding teaching and mentoring. She earlier received the 2012 Outstanding Mentor Award from the UC Davis Consortium for Women and Research.
Luckhart, who joined the UC Davis faculty in 2004 from Virginia Tech, received her master's degree in entomology from Auburn University, and her doctorate in entomology from Rutgers, the State University of New Jersey.
Access the website for upcoming PICN seminars.
The event will take place in MU II (second floor) and is free and open to the public.
It's being held "to increase awareness among the general public about malaria, one of the world's oldest and deadliest diseases, as well as vector-borne problems at home in California," said medical entomologist Gregory Lanzaro, professor in the Department of Pathology, Microbiology and Immunology, UC Davis School of Veterinary Medicine.
Malaria "is a leading cause of death and disease in many developing countries, where young children and pregnant women are the groups most affected," the Center for Disease Control and Prevention (CDC) points out, citing these figures from the World Health Organization's World Malaria Report 2013 and the Global Malaria Action Plan:
- 3.4 billion people (half the world's population) live in areas at risk of malaria transmission in 106 countries and territories
- In 2012, malaria caused an estimated 207 million clinical episodes, and 627,000 deaths. An estimated 91% of deaths in 2010 were in the African Region.
The most vulnerable groups, CDC says, are young children, who have not yet developed partial immunity to malaria; pregnant woman, whose immunity is decreased by pregnancy, especially during the first and second pregnancies; and travelers or migrants coming from areas with little or no malaria transmission, who lack immunity.
The schedule for the UC Davis Malaria Awareness Day:
- 10 to 10:30 am.: Coffee/social/posters
- 10:30 to 10:50: "General Malaria Biology" by medical entomologist Gregory Lanzaro, professor, Department of Pathology, Microbiology and Immunology, UC Davis School of Veterinary Medicine.
- 10:50 to 11:20: Conducting Field Research in Rural Africa" by medical entomologist Anthony Cornel, associate professor, UC Davis Department of Entomology and Nematology and based at the UC Kearney Agriculture and Research Center, Parlier
- 11:10 to 11:30: "Malaria Parasites in the Mosquito" by molecular biologist Shirley Luckhart, professor, UC Davis Department of Medical Microbiology and Immunology and an adjunct professor in the Department of Entomology and Nematology
- 11:30 to 11:50: "Mosquito-Borne Viral Diseases" by medical entomologist Chris Barker, assistant adjunct professor and assistant research scientist, UC Davis Department of Pathology, Microbiology and Immunology
- 11:50 to 12:10: "Disease Transmission by Non-Mosquito Vectors" by epidemiologist/veterinarian and disease ecologist Janet Foley, professor, UC Davis Department of Medicine and Epidemiology
- 12:10 to 1:30: A free lunch will be provided, but reservations must be made by April 21 to Youki Kevin Yamasaki at email@example.com.