University of California
Dev Test!

Calag Archive

Calag Archive

Sidebar: IR-4 Project targets specialty crops

Share using any of the popular social networks Share by sending an email Print article
Share using any of the popular social networks Share by sending an email Print article

Authors

Robert E. Holm
Daniel Kunkel

Publication Information

California Agriculture 58(2):110-111.

Published April 01, 2004

PDF  |  Citation  |  Permissions

Author Affiliations show

Full text

Pesticide applications for “minor” or “specialty” crops — typically those grown on less than 300,000 acres nationwide — often do not get the full support of product registrants because the potential economic benefits are perceived as much more limited than for applications targeting crops grown on large acreages, such as soybeans and field corn. The IR-4 Project is a unique partnership of researchers, producers, the crop-protection industry and federal agencies designed to increase pest-management options for specialty crops, which include vegetables, fruits, nuts, herbs, nursery crops and flowers. (Most of the crops grown in California fit into this category.)

With funding from the U.S. Department of Agriculture, state agencies, commodity groups and other industry sources, IR-4 researchers and cooperators generate field and laboratory residue data, which are submitted to the U.S. Environmental Protection Agency (EPA) to secure regulatory clearances for using safer pest-control techniques on specialty crops. Projects are prioritized based on requests from growers, commodity groups, and USDA and land-grant university researchers. Since 1963, IR-4 has contributed to more than 7,300 regulatory clearances for specialty crops.

In 1996, IR-4 responded to the federal Food Quality Protection Act (FQPA) by shifting its strategy from product defense (support for older pesticides needing reregistration) to working with reduced-risk/safer chemistries and biopesticides. The program also expanded its Good Laboratory Practices (GLPs) efforts, started a Methyl Bromide Alternatives Program and initiated a pilot program to support new transgenic horticultural crops. Because they are also grown on smaller acreages, transgenic horticultural crops face many of the same regulatory hurdles as uses on conventional specialty crops.

Focus on herbicide tolerance

The IR-4 team initially identified herbicide tolerance and insect resistance as potential opportunities for assisting transgenic specialty crops through the regulatory review process. It then narrowed down the focus to herbicide tolerance, recognizing that the FQPA could possibly limit the use of several key herbicides for vegetables due to regulatory concerns about toxicology and groundwater contamination. The other justification for focusing on herbicide tolerance was that the newer herbicides in the development pipeline for major crops had limited tolerance on specialty crops, prompting companies to restrict their uses on vegetables due to product liability concerns.

Sweet corn.

IR-4's first transgenic project was the result of research conducted by Gordon Harvey at the University of Wisconsin, who was looking for alternatives to the use of atrazine — a potential groundwater contaminant — in Wisconsin sweet-corn production. Harvey conducted studies on glufosinate-tolerant (Liberty Link) sweet corn and demonstrated excellent weed control. The commercial varieties linked the Bt gene with the glufosinate-tolerant gene to provide additional protection against corn borer and corn earworm, two major sweet-corn pests.

Matt Hengel, regional laboratory coordinator of the IR-4 Western Region, tests hops residue at the UC Davis Department of Environmental Toxicology.

Matt Hengel, regional laboratory coordinator of the IR-4 Western Region, tests hops residue at the UC Davis Department of Environmental Toxicology.

IR-4 then facilitated the residue assessment programs required by EPA in 1997, 1998 and 1999. As a result, EPA granted Section 18 “emergency use” permits for the herbicide-tolerant sweet corn in Wisconsin, Minnesota and Michigan in 1999 and 2000. However, due to concerns about consumer acceptance expressed by sweet-corn processors, no significant commercial acreages of these varieties were planted in 2001 and 2002. Nonetheless, IR-4 submitted a complete registration package to EPA for glufosinate-tolerant sweet corn in 2003.

Lettuce.

IR-4's other herbicide transgenic project was glyphosate-tolerant (Roundup Ready) lettuce. IR-4 staff met with Seminis Vegetable Seeds (licensee of transformation technology) and Monsanto (glyphosate registrant and gene technology licensor) in 1998 to discuss potential technology applications. The project was placed on the IR-4 30-month “fast track,” with submission to the EPA scheduled for 2001. The program was a cooperative partnership between Seminis Vegetable Seeds (seeds and technology support), Monsanto (residue analysis and technical support) and IR-4 (field residue program, project management and petition preparation and submission).

However, in 2000 several grower groups expressed reservations about the program primarily due to concerns about public acceptance, leading the partners to slow the program down. During this period, field results from several university researchers demonstrated excellent weed control in glyphosate-tolerant lettuce, resulting in reduction of hand-hoeing costs. It is still not certain when or if IR-4 will submit a registration package to EPA.

Future directions

IR-4 cannot take on additional specialty-crop biotechnology projects without new funding from the USDA (Agricultural Research Service and Cooperative State Research, Education, and Extension Service) and support from IR-4 management and stakeholders. Current funding is just adequate to cover the existing core programs of reduced-risk chemistries, biopesticides, ornamentals and methyl bromide alternatives. Additional funding from Congress or other sources (either public or private) would be necessary. IR-4's core competencies are in field residue studies and chemical laboratory analyses conducted under GLPs. Safety and environmental testing on specialty crops, especially allergenicity testing of newly expressed proteins in transgenic crops, is well beyond IR-4's existing capabilities.

Under current and proposed regulatory guidelines, the best approach for such testing might be to seek approval first in major acreage row crops such as corn, cotton, soybeans and rice, and allow those approvals apply to specialty-crop uses, as was the case for Bt sweet corn following the approval of Bt field corn. Of course, this approach is limited to traits that are applicable in both agronomic and horticultural crops, and will likely exclude many traits directed toward output quality.

The interagency IR-4 program evaluates the safety of agricultural chemicals intended for use on specialty crops. In Salinas, Agricultural Research Service agronomist Sharon Benzen displays broccoli grown in test plots, which will be used to determine pesticide residue levels.

The interagency IR-4 program evaluates the safety of agricultural chemicals intended for use on specialty crops. In Salinas, Agricultural Research Service agronomist Sharon Benzen displays broccoli grown in test plots, which will be used to determine pesticide residue levels.

IR-4 management and stakeholder support issue is even more difficult, as they are not in unanimous support of developing agricultural biotechnology, principally due to consumer concerns in Europe and to a lesser extent the United States. In the future, the IR-4 framework could be useful to address the pest-control needs of horticultural and other specialty crops via plant biotechnology, once a consensus is reached that they are cost-effective and safe for the environment and consumers.

Return to top

Sidebar: IR-4 Project targets specialty crops

Robert E. Holm, Daniel Kunkel
Webmaster Email: bjnoel@ucanr.edu

Sidebar: IR-4 Project targets specialty crops

Share using any of the popular social networks Share by sending an email Print article
Share using any of the popular social networks Share by sending an email Print article

Authors

Robert E. Holm
Daniel Kunkel

Publication Information

California Agriculture 58(2):110-111.

Published April 01, 2004

PDF  |  Citation  |  Permissions

Author Affiliations show

Full text

Pesticide applications for “minor” or “specialty” crops — typically those grown on less than 300,000 acres nationwide — often do not get the full support of product registrants because the potential economic benefits are perceived as much more limited than for applications targeting crops grown on large acreages, such as soybeans and field corn. The IR-4 Project is a unique partnership of researchers, producers, the crop-protection industry and federal agencies designed to increase pest-management options for specialty crops, which include vegetables, fruits, nuts, herbs, nursery crops and flowers. (Most of the crops grown in California fit into this category.)

With funding from the U.S. Department of Agriculture, state agencies, commodity groups and other industry sources, IR-4 researchers and cooperators generate field and laboratory residue data, which are submitted to the U.S. Environmental Protection Agency (EPA) to secure regulatory clearances for using safer pest-control techniques on specialty crops. Projects are prioritized based on requests from growers, commodity groups, and USDA and land-grant university researchers. Since 1963, IR-4 has contributed to more than 7,300 regulatory clearances for specialty crops.

In 1996, IR-4 responded to the federal Food Quality Protection Act (FQPA) by shifting its strategy from product defense (support for older pesticides needing reregistration) to working with reduced-risk/safer chemistries and biopesticides. The program also expanded its Good Laboratory Practices (GLPs) efforts, started a Methyl Bromide Alternatives Program and initiated a pilot program to support new transgenic horticultural crops. Because they are also grown on smaller acreages, transgenic horticultural crops face many of the same regulatory hurdles as uses on conventional specialty crops.

Focus on herbicide tolerance

The IR-4 team initially identified herbicide tolerance and insect resistance as potential opportunities for assisting transgenic specialty crops through the regulatory review process. It then narrowed down the focus to herbicide tolerance, recognizing that the FQPA could possibly limit the use of several key herbicides for vegetables due to regulatory concerns about toxicology and groundwater contamination. The other justification for focusing on herbicide tolerance was that the newer herbicides in the development pipeline for major crops had limited tolerance on specialty crops, prompting companies to restrict their uses on vegetables due to product liability concerns.

Sweet corn.

IR-4's first transgenic project was the result of research conducted by Gordon Harvey at the University of Wisconsin, who was looking for alternatives to the use of atrazine — a potential groundwater contaminant — in Wisconsin sweet-corn production. Harvey conducted studies on glufosinate-tolerant (Liberty Link) sweet corn and demonstrated excellent weed control. The commercial varieties linked the Bt gene with the glufosinate-tolerant gene to provide additional protection against corn borer and corn earworm, two major sweet-corn pests.

Matt Hengel, regional laboratory coordinator of the IR-4 Western Region, tests hops residue at the UC Davis Department of Environmental Toxicology.

Matt Hengel, regional laboratory coordinator of the IR-4 Western Region, tests hops residue at the UC Davis Department of Environmental Toxicology.

IR-4 then facilitated the residue assessment programs required by EPA in 1997, 1998 and 1999. As a result, EPA granted Section 18 “emergency use” permits for the herbicide-tolerant sweet corn in Wisconsin, Minnesota and Michigan in 1999 and 2000. However, due to concerns about consumer acceptance expressed by sweet-corn processors, no significant commercial acreages of these varieties were planted in 2001 and 2002. Nonetheless, IR-4 submitted a complete registration package to EPA for glufosinate-tolerant sweet corn in 2003.

Lettuce.

IR-4's other herbicide transgenic project was glyphosate-tolerant (Roundup Ready) lettuce. IR-4 staff met with Seminis Vegetable Seeds (licensee of transformation technology) and Monsanto (glyphosate registrant and gene technology licensor) in 1998 to discuss potential technology applications. The project was placed on the IR-4 30-month “fast track,” with submission to the EPA scheduled for 2001. The program was a cooperative partnership between Seminis Vegetable Seeds (seeds and technology support), Monsanto (residue analysis and technical support) and IR-4 (field residue program, project management and petition preparation and submission).

However, in 2000 several grower groups expressed reservations about the program primarily due to concerns about public acceptance, leading the partners to slow the program down. During this period, field results from several university researchers demonstrated excellent weed control in glyphosate-tolerant lettuce, resulting in reduction of hand-hoeing costs. It is still not certain when or if IR-4 will submit a registration package to EPA.

Future directions

IR-4 cannot take on additional specialty-crop biotechnology projects without new funding from the USDA (Agricultural Research Service and Cooperative State Research, Education, and Extension Service) and support from IR-4 management and stakeholders. Current funding is just adequate to cover the existing core programs of reduced-risk chemistries, biopesticides, ornamentals and methyl bromide alternatives. Additional funding from Congress or other sources (either public or private) would be necessary. IR-4's core competencies are in field residue studies and chemical laboratory analyses conducted under GLPs. Safety and environmental testing on specialty crops, especially allergenicity testing of newly expressed proteins in transgenic crops, is well beyond IR-4's existing capabilities.

Under current and proposed regulatory guidelines, the best approach for such testing might be to seek approval first in major acreage row crops such as corn, cotton, soybeans and rice, and allow those approvals apply to specialty-crop uses, as was the case for Bt sweet corn following the approval of Bt field corn. Of course, this approach is limited to traits that are applicable in both agronomic and horticultural crops, and will likely exclude many traits directed toward output quality.

The interagency IR-4 program evaluates the safety of agricultural chemicals intended for use on specialty crops. In Salinas, Agricultural Research Service agronomist Sharon Benzen displays broccoli grown in test plots, which will be used to determine pesticide residue levels.

The interagency IR-4 program evaluates the safety of agricultural chemicals intended for use on specialty crops. In Salinas, Agricultural Research Service agronomist Sharon Benzen displays broccoli grown in test plots, which will be used to determine pesticide residue levels.

IR-4 management and stakeholder support issue is even more difficult, as they are not in unanimous support of developing agricultural biotechnology, principally due to consumer concerns in Europe and to a lesser extent the United States. In the future, the IR-4 framework could be useful to address the pest-control needs of horticultural and other specialty crops via plant biotechnology, once a consensus is reached that they are cost-effective and safe for the environment and consumers.

Return to top


University of California, 2801 Second Street, Room 184, Davis, CA, 95618
Email: calag@ucanr.edu | Phone: (530) 750-1223 | Fax: (510) 665-3427
Website: https://calag.ucanr.edu