Her research expertise involves molecular genetics of animal behavior, circadian rhythm biology, and posttranslational regulation of proteins.
By using Drosophila melanogaster as a model to study the mechanisms that regulate circadian clocks, Chiu has discovered new insights into the function of key proteins that control animal circadian clocks. In particular, she has identified new mechanisms that slow down or speed up the internal clock of fruit flies and mechanisms that allow the internal clock to interpret food as timing cues--research that could help lead the way to alleviate human circadian disorders.
“Dr. Chiu is a prolific, phenomenal and talented scholar whose research is innovative, cutting-edge and groundbreaking,” said Helene Dillard, dean of the College of Agricultural and Environmental Sciences.
Steve Nadler, professor and chair of the Department of Entomology and Nematology, describes her as “a rising star.”
In announcing the Chancellor's Fellows, Chancellor Gary S. May said: “They've clearly made a mark both at UC Davis and within the academy generally. I have no doubt their contributions will continue to grow.” Each will retain the title for five years and receive a prize of $25,000 earmarked for research or scholarly work. Private donations to the UC Davis Annual Fund and the UC Davis Parents' Fund finance the program.
Chiu joined the Department of Entomology and Nematology in 2010 as an assistant professor and advanced to associate professor and vice chair in 2016. She received her bachelor's degree in biology and music from Mount Holyoke College, Mass., and her doctorate in molecular genetics in 2004 from New York University, New York. She served as a postdoctoral fellow from 2004 to 2010 in chronobiology (biological rhythms and internal clocks)--molecular genetics and biochemistry--at the Center for Advanced Biotechnology and Medicine, at Rutgers, the State University of New Jersey.
Major grants from the National Institutes of Health and the National Science Foundation fund Chiu's biological rhythms research.
In addition to her research in biological rhythms, Chiu also aims to leverage her expertise in genomics to address key issues in global food security. She is the principal investigator (PI) or co-PI on six grant awards from the State of California to research various fruit crops damaged by the spotted-wing Drosophila. At the time of her nomination, her publication record included 41 journal publications and book chapters, one U.S. Patent, and more than 3,235 journal citations (Google Scholar).
Chiu targets the spotted wing drosophila, Drosophila suzukii, first detected in North America in central California in August 2008. A native of Southeast Asia, the invasive species has already caused billions of dollars in damage to U.S. agriculture. Chiu took the lead role in sequencing the genome and is now heavily involved in finding new and more sustainable strategies to control the pest.
Chiu instigated the drive to obtain genomic data prior to its adaptation to a variety of local environments, which can differ in climate, pesticide use, natural enemies and types of fruits available. She played a leading role in establishing the SpottedWingFlyBase, a publicly available web portal documenting a variety of genomic databases for this species.
Chiu co-founded and co-directs (with professor Jay Rosenheim and associate professor Louie Yang) the campuswide Research Scholars Program in Insect Biology, launched in 2011 to provide undergraduates with a closely mentored research experience in biology. The program's goal is to provide academically strong and highly motivated undergraduates with a multi-year research experience that cultivates skills that will prepare them for a career in biological research.
Under her tutelage, many of Chiu's students are first authors of publications in prestigious journals. She continues to provide guidance and advice to undergraduate and graduate students and those who have embarked on their careers.
Former UC Davis graduate student Kelly Hamby, now assistant professor/Extension specialist in the Department of Entomology, University of Maryland, said Chiu “is so generous of her time and advice. Her office is always open to students, whether they are visiting high school students, undergraduates, or graduate students, her own students or someone else's. She carefully guides students throughout their experiments, directly providing technical training—side by side at the bench—while developing their critical thinking and communication skills. Joanna not only imparts excellent analytic and laboratory molecular skills to her students, but also commits to providing ongoing professional advice and development. Joanna's mentorship continues long after graduate and she leaves a lasting impression on students.”
“Joanna's teaching philosophy is clearly targeted towards the professional development of her students, modeling assignments on the activities of practicing scientists,” Hamby added.
The previous recipient from the Department of Entomology and Nematology was pollination ecologist Neal Williams, now a professor.
See list of this year's Chancellor's Fellows on UC Davis Dateline.
Pollination ecologist Neal Williams, UC Davis Department of Entomology and Nematology professor, is organizing and chairing the symposium, which is scheduled for Tuesday afternoon, April 2 in the Hyatt Regency Mission Bay Spa and Marina.
“The symposium will include scientific contributions from leaders in the fields of bee ecology, conservation and pollination,” announced Williams. “All are individuals whose work and specialty have been influenced by Robbin and his research program."
The scientists speaking, in addition to emcee Williams, include:
- Claire Kremen, University of British Columbia, formerly of UC Berkeley
- James Strange, USDA's Agricultural Research Service
- Heidi Dobson, Whitman College, Walla Walla, Wash.
- Gretchen Lebuhn, San Francisco State University
- Richard Hatfield, Xerces Society for Invertebrate Conservation
- Terry Griswold, USDA's Agricultural Research Service
- Leslie Saul-Gershenz, UC Davis
- Gordon Frankie, UC Berkeley
“The symposium will be followed by a social time during which hope to share our gratitude with Robbin for his lifetime of work, mentoring and friendship,” Williams said.
Thorp, a member of the UC Davis entomology faculty for 30 years, from 1964-1994, achieved emeritus status in 1994 but has continued to engage in research, teaching and public service. In his retirement, he co-authored two books Bumble Bees of North America, an Identification Guide (Princeton University, 2014) and California Bees and Blooms, A Guide for Gardeners and Naturalists (Heyday, 2014).
Thorp, a tireless advocate of pollinator species protection and conservation, is known for his expertise, dedication and passion in protecting native pollinators, especially bumble bees, and for his teaching, research and public service. He is an authority on pollination ecology, ecology and systematics of honey bees, bumble bees, vernal pool bees, conservation of bees, contribution of native bees to crop pollination, and bees of urban gardens and agricultural landscapes. He is active in research projects and open houses at the Bohart Museum of Entomology.
Thorp received his bachelor of science degree in zoology (1955) and his master's degree in zoology (1957) from the University of Michigan, Ann Arbor. He earned his doctorate in entomology in 1964 from UC Berkeley, the same year he joined the UC Davis entomology faculty. He taught courses from 1970 to 2006 on insect classification, general entomology, natural history of insects, field entomology, California insect diversity, and pollination ecology.
Every summer since 2002, Thorp has volunteered his time and expertise to teach at The Bee Course, an annual workshop sponsored by the American Museum of Natural History and held at the Southwestern Research Station, Portal, Ariz. The intensive 9-day workshop, considered the world's premiere native bee biology and taxonomic course, is geared for conservation biologists, pollination ecologists and other biologists who want to gain greater knowledge of the systematics and biology of bees.
An authority on Franklin's bumble bee, Bombus franklini, Thorp has monitored the bumble bee population since 1998 in its narrow distribution range of southern Oregon and northern California. He has not seen it since 2006 and it is feared extinct. In August of 2016 a documentary crew from CNN, headed by John Sutter followed him to a meadow where Thorp last saw Franklin's bumble bee. He wrote about Thorp, then 82, in a piece he called "The Old Man and the Bee," a spinoff of Ernest Hemingway's "The Old Man and the Sea."
Thorp was instrumental in placing the bumble bee on the Red List of Threatened Species of the International Union for Conservation of Nature and Natural Resources (IUCN). Long active in the North America IUCN Bumblebee Specialist Group, Thorp served as its regional co-chair, beginning in 2011.
Thorp was named a fellow of the California Academy of Sciences, San Francisco in 1986; recipient of the Edward A. Dickson Emeriti Professorship of UC Davis in 2010; and recipient of the UC Davis Distinguished Emeritus Award in 2015. Other honors include: member of the UC Davis Bee Team that won PBESA's Team Award in 2013. In addition, he is a past president (2010-2011) of the Davis Botanical Society, and former chair (1992-2011) of the Advisory Committee for the Jepson Prairie Reserve, UC Davis/Natural Reserve System.
Since its inception, Thorp has been involved in the Häagen-Dazs Honey Bee Haven, a half-acre bee garden on Bee Biology Road operated by the UC Davis Department of Entomology and Nematology, installed in 2009. To establish a baseline, he began monitoring the site for bees in 2008. He has since detected more than 80 species of bees.
Born Jan. 30, 1951 in Hong Kong and fondly known as “Amazing Grace,” she received her doctorate at UC Davis in 1983 with major professor Hammock, now a UC Davis distinguished professor who holds a joint appointment with the Department of Entomology and Nematology and the UC Davis Comprehensive Cancer Center.
Her husband of 41 years, Davy Jones, a longtime professor in the UK Department of Toxicology and Cancer Biology, received his doctorate from UC Davis, studying with major professor Jeffrey Granett of the then Department of Entomology.
Hammock described Grace Jones as a hard-working scientist with “amazing skill and creative insight.”
“Following her research at Texas A&M University, Grace joined my lab in the 1970s at UC Riverside and then finished her PhD at Davis in 1983,” recalled Hammock, a member of the UC Riverside faculty from 1975 to 1980, when he accepted a joint-faculty appointment in toxicology and entomology at UC Davis.
“She asked how juvenile hormone regulated the development of moth larvae that are serious agricultural pests,” Hammock said. “She also found two parasites, one of which sped up host larval development and the other of which slowed host larval development. She found that both parasitoids were manipulating the host insect endocrine system to their benefit. Endocrine regulation of insect development was a theme of Grace's whole career which she pursued with amazing skill, hard work and creative insight.”
Longtime friend and colleague Lynn Riddiford, emerita professor of biology at the University of Washington, Seattle, who worked with Grace Jones on a National Science Foundation grant, praised her as “a creative and imaginative scientist.”
“Her research focused on the action of juvenile hormone (JH), a key hormone regulating metamorphosis in insects,” Riddiford said. “Early on Grace studied the molecular mechanisms involved in the regulation by JH of several proteins in the cabbage looper, Trichoplusia ni—the JH-inducible JH esterase that breaks down JH and several JH-suppressible hemolymph storage proteins. Her work was always careful and thorough and contributed significantly to the field.”
Riddiford said that “Grace became intrigued by the idea that Ultraspiracle (USP), the heterodimeric partner of the ecdysone receptor (EcR), might be the long-sought JH receptor. She pursued this line of research with rigor, and later found that USP bound methyl farnesoate, the immediate precursor of JH, with the high affinity typical for hormone receptors. Furthermore, she showed that the methyl farnesoate-USP complex was critical for the larval-pupal transformation in Drosophila. Even though her initial idea that USP was the JH receptor proved wrong, her work stimulated the field and resulted in a deeper understanding of the factors controlling metamorphosis in Drosophila.”
Riddiford added: “Grace will be especially remembered for her amazing drive and determination to forge ahead with her science and to continue to make significant contributions despite the disabilities engendered by her stroke.” (See research publications)
Keith Wing, Hammock's second doctoral student who went on to become a senior research associate at Rohm and Haas and DuPont, and is now a consultant, remembered her as “a cheerful, hard-working colleague and friend, and wife of Dr. Davy Jones, University of Kentucky. A few of us spent many a late night studying juvenile hormone esterase and binding proteins at UC Riverside and Davis in lepidopteran larvae, trying to help the lab piece together the story of how JH metabolism and transport helped to regulate insect metamorphosis.”
“We shared everything and always helped each other out,” Wing said. “Grace went on to focus on this in much greater detail, including exploration into insect hormone receptors and regulation. She was an incredibly dedicated researcher who contributed a lot to the field."
Grace Jones received her bachelor's degree in biology in 1973 from Belmont (N.C.) Abbey College, and her master's degree in biology in 1974 from Jacksonville (Ala.) State University. She did post graduate research at Texas A&M in insect physiology and endocrinology before joining the Hammock lab in UC Riverside (1979-80). After receiving her doctorate in 1983 from UC Davis, she headed to Harvard University's Medical School as a visiting scholar in the Department of Cell Biology and Department of Pathology, working there from 1989 to 2000. Her career then included visiting scientist at Massachusetts Institute of Technology's Department of Biology and a visiting professor at Baylor College of Medicine, where she specialized in stem cell research.
The UC Davis alumnus joined the UK Department of Entomology in 1984 as an assistant research professor, studying insect biochemistry and molecular biology. She was promoted to associate research professor in 1990, and then switched to UK's School of Biological Sciences, becoming an assistant professor of molecular and cellular biology in 1991; an associate professor in 1993; and a full professor in 1999.
"Dr. Jones was a superb, internationally recognized scientist, even as her health declined over the past 18 years, but she continued to work on teaching and research throughout," wrote UK Department of Biology chair Vincent Cassone on a web page memoralizing her. "Over the course of her research career, Dr. Jones had received millions of grant dollars for her important studies from the National Institutes of Health and National Science Foundation, and published more than 100 research articles in prestigious journals such as the Proceedings of the National Academy of Sciences, USA, Journal of Biological Chemistry, and Molecular and Cellular Endocrinology. She and Davy also received a patent in 2007 for a method to identify drugs that interact with insect nuclear receptors, which could be used for biological control of pest species."
"Over the years, students have expressed great admiration and love for Professor Jones in letters and emails, and eminent scientists have expressed their high regard for her work," Cassone wrote. "A Grace Jones Memorial Fund for Family Support has been set up. Donations can be sent to the UK College of Health Science c/o Loralyn Cecil, 900 South Limestone 124E, Lexington, KY 40508 or online at https://karrn.org/. Her infectious smile will be missed in the halls of Biology, as she had her daily walks, arm in arm, color-coordinated with her husband, Davy, a testament to devotion and love."
Davy Jones notified his wife's friends and colleagues, including Hammock, of her death with an email, “Butterfly has flown on.” He attached a photo of Grace and a blue morpho butterfly.
She died in his arms, as this song, “Amazing Grace,” played softly in the room, he wrote.
“UC Riverside, UC Davis and the field lost a wonderful colleague and we have all lost a dear friend,” Hammock told him.
Time's fun when you're studying flies!
Student fly researchers greeted guests and explained their work at the Bohart Museum of Entomology open house held last Saturday, Jan. 12.
The event, which took place from 1 to 4 p.m. in Room 1124 of the Academic Surge Building on Crocker Lane, drew more than 150 visitors, despite competition with the televised National Football League playoffs and other activities.
The theme, "Time's Fun When You're Studying Flies," was a take-off of "Time flies when you're having fun."
"Despite the lovely weather, visitors spent a long time at the museum talking with our department's up and coming researchers," said Tabatha Yang, the Bohart Museum education and outreach coordinator. "Visitors learned about various research on flies that occurs in our department from evolution to geography to circadian rhythms."
Five scientists from the Joanna Chiu lab discussed their fruit fly research. They were graduate students Christine Tabuloc, Yao Cai and Xianhui "Nitrol" Liu, and undergraduate students Cindy Truong and Christopher Ochoa.
The Joanna Chiu lab currently has 4 PhD students (3 from Entomology and 1 from Genomics and Genetics), 6 undergraduate students (3 from Underrepresented Minorities or URM) undergraduate research programs), 1 postdoc, and 1 visiting graduate student from China.
Others fly researchers participating:
- Graduate student Caroline Wright Larsen of the James R. Carey Lab; she studies non-tephrid flies, including the Mediterranean fruit fly
- Graduate students Socrates Letana and Charlotte Herbert Alberts of the Lynn Kimsey Lab; Letana studies botflies, and Alberts, assassin flies
- Graduate student Alex Dedmon of the Robert Kimsey lab and UC Davis graduate Danielle Wishon; they specialize in forensic entomology
"They all did an excellent job engaging the public with thoughtful slide shows, images, and specimens," Yang said. "They truly communicated their enthusiasm for science."
The next open house will be Saturday, Feb. 16, when the Bohart Museum will be open as part of campuswide Biodiversity Museum Day.
Upcoming open houses:
- "Eight-Legged Wonders" (spider theme, featuring the work of the Jason Bond lab) on Saturday, March 9 from 1 to 4 p.m.
- UC Davis Picnic Day on Saturday, April 13 from 10 to 3 p.m.
The Bohart Museum, directed by Lynn Kimsey, professor of entomology, houses nearly eight million insect specimens, plus a year-around gift shop and a live "petting zoo" that includes Madagascar hissing cockroaches, stick insects, tarantulas and praying mantids. The gift shop is stocked with newly published calendars, books, jewlery, t-shirts, insect-collecting equipment, insect-themed candy, and stuffed animals. UC Davis entomologist Richard “Doc” Bohart (1913-2007) founded the museum in 1946.
The Bohart is open to the general public Mondays through Thursdays, from 9 a.m. to noon and from 1 to 5 p.m., plus occasional, weekend open houses. Admission is free. Further information is available on the Bohart Museum website at http://bohart.ucdavis.edu/ or contact (530) 753-0493 or email@example.com.
Now, newly published research on ovarian cancer, involving an anti-inflammatory compound discovered and developed in the Bruce Hammock lab at the University of California, Davis, and tested at Harvard Medical School on mice models, indicates that the compound not only suppresses inflammation but reduces cancer growth, acting as a “surge protector.”
“We are excited about this research and its potential,” said Hammock, a UC Davis distinguished professor who holds a joint appointment with the Department of Entomology and Nematology and the UC Davis Comprehensive Cancer Center. “Chemotherapy and surgery, the mainstays of conventional cancer treatment, can act as double-edged swords. It is tragic that the very treatments used to cure cancer are helping it to survive and grow.”
The research is a “novel approach to suppressing therapy-induced tumor growth and recurrence,” said the 13-member team from Harvard Medical School/Beth Israel Deaconess Medical Center (BIDMC), UC Davis, Institute of Systems Biology of Seattle, and Emory University School of Medicine of Atlanta.
Their paper, “Suppression of Chemotherapy-induced Cytokine/Lipid Mediator Surge and Ovarian Cancer by a Dual Cox-2, sEH Inhibitor,” appears today in the Proceedings of the National Academy of Sciences (PNAS).
“To prevent tumor-recurrence after therapy, it will be critical to neutralize the inherent tumor-promoting activity of therapy-generated debris,” said lead author Allison Gartung of Harvard Medical School/BIDMC. “Our results indicate that a dual COX-2/sEH inhibitor may offer a novel alternative to protect the body from a debris-mediated inflammatory response.”
Gartung said that the study confirmed that chemotherapy-killed ovarian cancer cells “induce surrounding immune cells called macrophages to release a surge of cytokines and lipid mediators that create an optimal environment for tumors to survive and grow.”
The team treated the mice models with a dual lipid pathway inhibitor discovered several years ago in the Hammock lab. It integrates two anti-inflammatory drugs (COX-2 inhibitor and soluble expoxide hydrolase (sEH) inhibitor) into a single molecule with the aim of reducing tumor angiogenesis and metastasis.
Chemist Sung Hee Hwang of the Hammock lab developed the compound, known as PTUPB, for the study. “The dual inhibitor here follows earlier work we did with it, blocking breast and lung tumors in mice,” Hammock said. “PTUPB is already being clinically evaluated for its therapeutic properties in other diseases.” Chemist Jun Yang of the Hammock lab did the mass spectrometry, showing how stabilization of lipid mediators reduces cancer growth and metastasis.
Lead researcher Dipak Panigrahy, a former Harvard physician turned full-time researcher, described chemotherapy and surgery “as our best tools for front-line cancer therapy, but chemotherapy and surgery create cell debris that can stimulate inflammation, angiogenesis, and metastasis. Thus, the very treatment used by oncologists to try to cure cancer is also helping it survive and grow. Overcoming the dilemma of debris-induced tumor progression is critical if we are to prevent tumor recurrence of treatment-resistance tumors which lead to cancer therapy failure.”
The tumor cell debris generates a “cytokine surge” that can result in a perfect storm for cancer progression. “The dual inhibitor acts as a surge protector,” Panigrahy said.
Panigrahy, who led angiogenesis and cancer animal modeling in the laboratory of Judah Folkman, a leading cancer research laboratory, based the debris model on his mother's chemotherapy treatments, and dedicated the research to his mother and “all other women who lost their lives to ovarian cancer.” American Cancer Society statistics show that among women, ovarian cancer ranks fifth in cancer deaths. A woman's risk of ovarian cancer is about 1 in 78; every year more than 14,000 die from the disease.
“Traditional cancer therapy sets up a dilemma,” Panigrahy commented. “Yes, we need to kill cancer cells but the inevitable byproduct of successfully doing so also stimulates tumor regrowth and progression. The more tumor cells you kill, the more inflammation you create, which can inadvertently stimulate the growth of surviving tumor cells. Overcoming the dilemma of debris-induced tumor progression is paramount if we are to prevent tumor recurrence of treatment-resistant tumors – the major reason for failure of cancer therapy. Our studies potentially pave the path for a new strategy for the prevention and treatment of chemotherapy-induced resistance with potential to translate to the clinic. If successful, this approach may also allow us to reduce the toxic activity of current treatment regimens.”
“The collaborative work in this paper not only defines a common problem with current cancer therapy, but it actually offers a potential solution to reduce metastasis and tumor growth following therapy,” said Primo Lara Jr., director of the UC Davis Comprehensive Cancer Center and associate director of Translational Research. “I am pleased that our Center was involved in this exciting project and we hope we can be involved in translating this basic research to the clinic.”
Panigrahy said that non-steroidal anti-inflammatory drugs (NSAIDs), which include aspirin and ibuprofen, reduce pain, fever and inflammation “bit may have severe side effects including stomach and brain bleeding as well as severe cardiovascular and kidney toxicity. They also do not specifically enhance clearing of debris.”
“We are exploring all options to translate PTUPB to cancer patients especially in combination with current cancer therapies such as chemotherapy, radiation, immunotherapy, or surgery which either directly or indirectly may generate tumor cell debris,” Panigrahy said. “Our next step is to investigate whether our findings are consistent with clinical studies involving human cancer.”
The Hammock lab has been researching the sEH inhibitor for 50 years. As a graduate student at UC Berkeley, Hammock co-discovered the sEH inhibitor with fellow graduate student Sarjeet Gill, now a distinguished professor at UC Riverside.
"We have a series of papers largely in PNAS, with the Panigrahy group showing first our soluble epoxide hydrolase inhibitors block tumor growth and metastasis when used with omega3 fish oils or with COX inhibitors and the role for these compounds in regulating a number of mediators of cancer growth," Hammock said.
Multiple grants funded the research. Hammock, the 31-year director of the UC Davis Superfund Program, received funds the National Cancer Institute and the National Institute on Environmental Health Sciences. The Panigrahy laboratory is funded by the Credit Union Kids at Heart Team. Other grants came from the C. J. Buckley Pediatric Brain Tumor Fund, Molly's Magic Wand for Pediatric Brain Tumors, the Markoff Foundation Art-in-Giving Foundation, the Kamen Foundation, Jared Branfman Sunflowers for Life, and the Joe Andruzzi Foundation. An NIH T32-training grant funded Gartung's work.
Allison Gartung completed her doctorate at Wayne State University in 2016 and has since served as a postdoctoral research fellow at Harvard Medical School/BIDMC. Highly honored for her work, she won the highest award for a post-doctoral fellow (Santosh Nigam Award) at the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases, held in 2017 in Puerta Vallarta, Mexico. She served as a guest editor of a special double-issue of 24 invited world-experts in Cancer and Metastasis Reviews on Bioactive Lipids.
Dipak Panigrahy was accepted into medical school at Boston University at age 17. He trained in surgery with Dr. Roger Jenkins, who performed the first liver transplant in New England. Over the past decade, Panigrahy led angiogenesis and cancer animal modeling in the Judah Folkman laboratory. He joined the Beth Israel Deaconess Medical Center in 2013, and in 2014 was appointed assistant professor of pathology, and currently has a laboratory in the Center for Vascular Biology Research. Panigrahy is the expert on the team for preclinical tumor models and examining novel concepts for cancer therapy at the preclinical stage –the diversity of models he has created and worked with is unmatched.
Bruce Hammock, UC Davis distinguished professor, is the world expert and discoverer of the dual COX2-sEH inhibitor. He received his doctorate in entomology/toxicology from UC Berkeley and joined the UC Davis faculty in 1980. Highly honored by his peers, Hammock is a fellow of the National Academy of Inventors, which honors academic invention and encourages translations of inventions to benefit society. He is a member of the U.S. National Academy of Sciences, and the recipient of scores of awards, including the Bernard B. Brodie Award in Drug Metabolism, sponsored by the America Society for Pharmacology and Experimental Therapeutics; and the first McGiff Memorial Awardee in Lipid Biochemistry,
Mark Kieran of Bristol-Myers Squibb and Professor Vikas Sukhatme (Dean of Emory School of Medicine), both senior co-authors, are leading world-experts on personalized medicine approaches to support the treatment of cancer patients. Kieran is a leading oncologist with expertise in translating novel therapeutic modalities (beyond chemotherapy/irradiation) into the clinic. Plans for clinical trials involving PTUPB are underway.
Professor Sui Huang, with the Institute for Systems Biology (ISB), is known as the world's leading expert on systems biology and debris-induced tumor growth.